This year, Grey’s Anatomy celebrates its 20th anniversary. Since the medical series aired its first episode, hundreds of characters popped in and out every season, and a good number of them left Grey Sloan Memorial Hospital (previously called Seattle Grace Hospital) didn’t make it very far into the show’s 21 seasons. In a new interview with Entertainment Weekly, franchise creator Shonda Rhimes reveals that despite the high body count of the series, there is one death that she still hasn’t managed to get over: Denny Duquette’s (Jeffrey Dean Morgan).